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ON YOUR MARKS, GET SET… FIND !

TEST–Therapeutic research is a marathon. Finding a treatment that will improve or even correct the intellectual disability related to various genetic disorders including Down syndrome is an urgent matter.

The Foundation,  following the trail blazed by Professor Lejeune, is part of this race in the service of patients and future generations.

The research programs are comprised of fundamental research on cells, on test animals, and applied research on humans. The latter includes clinical research with hands-on programs like the Acthyf study, currently underway.

“We will find. It will take much less intellectual effort than sending a man to the Moon.”

Professor Jérôme Lejeune, about a cure for Down Syndrome (trisomy 21)

Progress for Everyone

WHEN RESEARCH EFFORTS AIMED AT A DISEASE BECOME PROGRESS FOR EVERYONE TO SHARE

Fundamental and clinical research produces scientific and medical information to better understand and treat many genetic intelligence disorders and other similar pathologies.

Patients with Down syndrome suffer from concomitant diseases.
Therefore, by studying, monitoring and treating their symptoms, healthcare professionals also make progress in understanding other illnesses: Alzheimers, diabetes, cancer, etc. The synergies between these medical fields are the focus of the research on genetic intelligence disorders: neurobiology, cancer, neuropsychology, dermatology, speech therapy, immunology, etc… The discovery of treatments for these illnesses will benefit this wide range of patients. Regarding Down syndrome for instance, many related diseases exist.

Objective

WHAT’S THE OBJECTIVE?

In France, the Jérôme Lejeune Foundation is one of the main proponents of research to improve intellectual abilities in patients with genetic diseases causing intellectual disabilities.

Who

WHO?

The Foundation’s scientific network includes numerous research laboratories as well as national and international industrial partners.

It has several roles: development of research programmes, support of research teams working on Down syndrome and other genetic diseases with intellectual disabilities, provision to the scientific community of research tools via platform creation and by leading research efforts on Down syndrome. To learn more, consult the Scientific Council annual report.

“That’s how research advances!”

How

HOW?

  • The Foundation provides financial support to several clinical studies, the results of which are eagerly awaited by the patients’ families. Specifically, for example, it is question of improving children’s psychomotor development by proposing treatment at as young an age as possible.
  • Since the Foundation’s founding, hundreds of scientific dossiers have been accepted and subsidised by donations. The Foundation finances each year almost 70 research projects throughout the world with almost 2 million Euros. These projects have resulted in more than 500 scientific publications.
  • This work is the practical expression of individual and collective efforts built up over the years by the Foundation, thanks to the support of its donors, to mobilize research efforts on genetic diseases with intellectual disabilities.
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